Using an iPhone app to develop new drugs
Students at Rice University have recently designed an
iPhone app that allows for an easier method of testing drug toxicity levels. They
did this using a specials kind of bioassay. A bioassay is a process used to
determine the potency of a substance on a living organism. This is essential for
developing new drugs and modifying existing ones. The project at Rice used a solution
of magnetic nano-particles which grab onto the cells being tested with the
developing drug and levitates them in the solution using a magnetic field. This
promotes the interactions of the cells and allows for a unique 3-D view which
makes them easier to study as they grow and divide. An iPhone that has the app
running is simply placed under a 96 well plate containing the cells in the
solution and a special lens, then set to take pictures at desired intervals of
time. “This literally collects about 100,000
data points during a 12-hour, overnight experiment,” explained one the
Rice students working on the project. The app then puts the data collected
through another analytic program. The end result is an organized array of
charts, graphs and time lapse shots which one can look at to get a better
understanding of the drug’s toxicity. This new process is expected to save
companies tens of millions for each drug. I was interested in this
article because I liked the idea of applying something like an iPod which are simple
to obtain and use, the applying it to do something complex.
http://news.rice.edu/2013/10/28/have-ipod-will-test-for-drug-toxicity/
http://news.rice.edu/2013/10/28/have-ipod-will-test-for-drug-toxicity/
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