Esophageal Sphincter Device for Gastroesophageal Reflux Disease

Gastro-oesophageal reflux disease (GERD), more commonly known as acid reflux, is a disease caused, in most cases, by relaxation of the sphincter.  Proton pump inhibitors are often used to stop secretions of hydrochloric acid by the parietal cells of the stomach. In some patients PPI's are not effective and patients will only see partial symptom relief.  This is due to the fact PPI's only target the acid secretions and not the underlying problem of the ineffective sphincter.  A magnetic device was created to improve barrier function of between the esophagus and stomach by modulating the resistance of the sphincter.

Studies showed the ligature placed around the lower esophageal sphincter prevented the upflow of gastric acid.  The magnetic device functions to provide extra resistance to the sphincter while continuing to allow the passing of food and accommodating for vomiting.  Needless to say as a BMEN major I found this article engaging, because it is in fact a fine product of biomedical engineering.


http://www.nejm.org/doi/full/10.1056/NEJMoa1205544