Fibronectin coating of oxygenator membranes enhances endothelial cell attachment
There has been recent testing on lining the materials used for oxygenation gas exchange membranes with different proteins in an effort to promote the attachment tan proliferation of arterial endotherlial cells. In this artical they mention that if you coat the material with fibronectin there is an increase in the number of endothelial cells that attach to it. In their experiment they tested for a period of four days and saw these results which is plenty long enough to look into using for our device design project for this semester. Also, the only materiel that had a positive test for confluent cell attachment was polydimethylsiloxane.
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