Monday, December 03, 2012

mRNA Flu Vaccine

Life long protection against the flu maybe possible

The discovery of a protein called protamine makes it possible for mRNA to exist without being destroyed in the blood. This will allow the immune system to incorporate the new mRNA as a protein signal against the flu.  DNA flu vaccines are being studied but these are unlikely to proceed to human trials due to the fear that cells may integrate the DNA vaccine into their DNA. mRNA also has the ability to survive as a freeze dried powder which will make shipment and production easier than current methods requiring refrigeration for the vaccine. mRNA also allows for the vaccine to trigger cell-mediated response along with the typical antibody response. This will allow for greater protection against the virus and quicker response to clear any infection of the virus that might get started.

As news of A&M's bioterror grant still fresh in our minds these kinds of vaccines maybe closer to us than we think.

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