Friday, September 28, 2012

VX-765 to Fight Epilepsy

Article link: http://www.nytimes.com/2012/06/05/health/research/new-epilepsy-tactic-fight-inflammation.html?pagewanted=all&_r=0

This is a new study on the treatment of epilepsy, what makes this study different is that it focuses on the small percent of the epileptic population that doesn't respond to standard epileptic medicine. This study targets the inflammation. This is because it is believed that the two, inflammation and seizures, are tied together. This study also tries to target and prevent any possible brain damage caused by epilepsy. Some of these seizures and inflammation can be so sever that the doctor has to preform a hemispherecotomy, which is where an entire semiphere of the brain is removed due to the inflammation caused from the seizures.

Dr. Vezzani has been testing a molecule called VX-765, this is known to disrupt the inflamation process and reduce the number of seizures by up to two thirds. When put into phase 2 of testing, subjects only began to experience progress right at the end of the study. And other current treatments, that are using strong steroids, have proven to have long term effects. Currently we are only able to fight the symptoms and not the actual disease, but we should see new science proving otherwise very soon.

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