Monday, September 10, 2012

The wound-healing and antioxidant effects of adipose-derived stem cells



The limited availability of human cells that are capable of self-renewal and differentiation is a barrier to the expansion of tissue engineering. However, in this article I learned that there is potential for ADSCs, adipose-derived stem cells, to solve this problem. ADSCs can be easily obtained from a human through liposuction of adipose tissue. The ADSCs can then be used to secrete various growth factors that control and manage damaged neighboring cells. Recently, ADSCs has been used for skin repair in animals. ADSC was able to stimulate the activation of dermal fibroblasts and keratinocytes. 

I found this article interesting because the idea of accelerated wound healing by injecting stem cells near the wound on the skin would mean a decrease in scars. I have a friend who had a wound on his knee that was so bad that he had to undergo plastic surgery to remove the scar. If ADSCs prove to be a solution to the problem of non-regenerative skin cells, wounds could heal more rapidly and leave less damaged tissue behind.

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