The wound-healing and antioxidant effects of adipose-derived stem cells
The limited availability of human
cells that are capable of self-renewal and differentiation is a barrier to the
expansion of tissue engineering. However, in this article I learned that there
is potential for ADSCs, adipose-derived stem cells, to solve this problem.
ADSCs can be easily obtained from a human through liposuction of adipose
tissue. The ADSCs can then be used to secrete various growth factors that
control and manage damaged neighboring cells. Recently, ADSCs has been used for
skin repair in animals. ADSC was able to stimulate the activation of dermal
fibroblasts and keratinocytes.
I found this article interesting
because the idea of accelerated wound healing by injecting stem cells near the wound on the skin would
mean a decrease in scars. I have a friend who had a wound on his knee that was
so bad that he had to undergo plastic surgery to remove the scar. If ADSCs
prove to be a solution to the problem of non-regenerative skin cells, wounds
could heal more rapidly and leave less damaged tissue behind.
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