Sunday, September 30, 2012

Brain tumor growth model


Having a good model of brain tumor growth pattern, as well as a mathematical equation based on the model, could help expedite image-guided surgery by decreasing the amount of time spent in the planning stage when surgeons must determine the size of a tumor before performing image-guided surgery. This paper suggests such a model and mathematical equation.

The general pattern of brain tumor growth is expressed on a slice by slice basis by the equation in the article. An existing model determines the instantaneous tumor area at any given point within a certain slice thickness, but no model exists to determine the volume of a tumor within and between slices. In a process that involved taking the integral of the existing equation, the authors were able to derive the equation for volume of a tumor within and between slices.

The validation design process of this equation involved two patients with similar circular tumors. In a five-step process, the results of the suggested model were accurate when compared to an existing model. The main benefit of the new model is that it indicates a quicker way to determine the volume of a tumor intra and inter slice can soon be developed.

Article:

http://iium.academia.edu/AbdulfattahAboaba/Papers/1896097/Brain_Tumor_Quantification_Equation

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