Nerve Cells Grow on Nanocellulose: Creation of a Three-dimensional Model of Brain

Nanocellulose is produced by bacteria spinning a structure of cellulose fibers or from isolation of wood pulp. Nanocellulose has successfully acted as a stimulus for neural network growth after an increase in the positive charge of the scaffold. This first step could expedite the formation of a three-dimensional model of the brain that could greatly enhance brain research for not only Alzheimer’s disease and Parkinson’s disease but many others.

Figure 1. The nanocellulose in the background is supporting the nerve cells where the yellow spots indicate functioning synapses and the red spots indicate destroyed synapses.

Figure 1 illustrates the ability to monitor the destruction of nerve cells that occur in Alzheimer’s disease.  Additionally, the next possible creation of pores in the nanocellulose would create an even more accurate model of the brain for comparison.  The artificial brain’s response to various pharmaceuticals will increase chances for successful development of treatment.  One possible experiment is to see the effect of patient’s spinal fluid on the health of nerve cells.

According to Paul Gatenholm there are several other applications for the nanocellulose. In fact, this newly opened door could lead up to the development of biocomputers, cartilage for artificial ears, and blood vessels. Could this nanocellulose help  form artificial kidneys?

Source :

http://www.sciencedaily.com/releases/2012/03/120319094757.htm
ScienceDaily –March 19, 2012

Leanne Kristek, VTPP 435-501