Saturday, March 03, 2012

Cure for Celiac Disease?




Celiac disease is an autoimmune and inflammatory condition. The protein gluten triggers the inflammation that damages the lining of the small intestines. Symptoms include bloating, cramping, gas, and constipation.

In a new study, researchers blocked IL-15 (a specific DNA sequence), and found that the symptoms were reversed in mice, allowing for them to eat the protein again. Interleukin 15 (IL-15) regulates T and natural killer (NK) cell activation and proliferation. Survival signals that maintain memory T cells in the absence of antigen are provided by IL-15. They are beginning to come up with pathways in order to block this element, increasing the tolerance for Gluten again.

In a second study by BMC Medicine, they are investigating the responses by CD, to determine the pathways that trigger the increased intestinal permeability, mucosal damage, and genetic predisposition. Their results find the cause for CD still unknown.

Some acne medications are being found that may be complicit with the onset of Celiac Disease. Do NOT take Retin-A and Accutane, since they have been identified as potential culprits for Celiac.



http://www.celiaccenter.org/documents/GlutenSensitivity2011.pdf

http://www.webmd.com/digestive-disorders/celiac-disease/news/20110208/new-treatment-for-celiac-disease

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