Saturday, April 30, 2011

A diabetes drug, sitagliptin, also has a potential to prevent diabetes

In this article, researches were searching for a way to prevent diabetes 2. As we know, diabetes 2 isn't a disease that appears over-night or is inherited like type 1. Rather it develops over a period of time. Thus, the goal of these researchers was to prevent prediabetes, the condition that essentially leads to type 2 diabetes. Experimental animal trials on the SHROB rat, a prediabetes like rat, showed that a drug named Sitagliptin was effective in lowering glucose levels after a meal while also raising the total output of insulin secreted by the pancreas. Essentially, these affects correct the developement of type 2 diabetes. In addition, this drug showed the ability to redistribute fat in the body from the abdomen. This result favors treatment on prediabetes patients and should help reduce cardiovascular risk. I chose this article because while studying for our second exam, I was reviewing kidney function where diabetes was mentioned as an instance where the kidneys are unable to reabsorb all of the glucose filtrated in the Bowman's capsule. Interestingly, if this drug is able to work on pantients, which only a clinical trial can prove, it would be an amazing break through for medicine.


http://www.breakthroughdigest.com/medical-news/a-diabetes-drug-sitagliptin-also-has-a-potential-to-prevent-diabetes/

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