Thursday, April 03, 2008

Video capsule may soon diagnose celiac disease

A new study in the American Journal of Gastroenterology has shown that villous atrophy in suspected cases of celiac disease can be detected by a new device, the video capsule enteroscopy.
Diagnosis of celiac disease is made by the identification of lesions in the mucosa of the small bowel. This is currently accomplished by an endoscopy of the upper gastrointestinal tract in which multiple duodenal biopsies are taken.

A team of researchers in Italy evaluated the effectiveness of video capsule enteroscopy (VCE) against the standard endoscopy of the upper GI with biopsies of the second portion of the duodenum in patients suspected of having celiac disease and found VCE to have a sensitivity of 87.5 percent.

The findings of this study are significant because it shows that VCE may offer an effective alternative to duodenal biopsy. The next step is to confirm these findings by completion of a larger, more comprehensive study.

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