Switching Bacteria Off May Be Possible with New Class of Antibiotic

One day in the future, infection may be fought by simply switching bacterial invaders off. At least, that's the promise of new technology out of a group at Yale University that's studying riboswitches- short sections of untranslated RNA that monitor small compounds in the cell-like nucleotides, amino acids and sugars-in order to control gene expression. This nascent technology, which is currently being tested on simple bacteria in the lab, may soon constitute a novel class of antibiotics, those wonderful "magic bullets" from the 20th century that suddenly are encountering resistance from evolving bacteria.

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