Proteins and Retina Deterioration
A recent study has shown that if light
sensitive proteins called channelrhodopsins, are introduced into the
retina then Retinitis Pigmentosa can be delayed or stopped.
In Retinitis Pigmentosa the retina deteriorates due to abnormalities
in the photoreceptors or the retinal pigment epithelium of the retina, this
disorder typically leads to progressive blindness. When a cell in the
retina contains channelrhodopsins the protein can be activated to exposure
to light, this causes neighboring cells to take over function of the
photoreceptors.
This method has been successful in resting vision
in mice but it has its limits in humans. The human eye has the ability to see
in anything from "weak starlight to glaring sunlight." However in
this procedure a patient would only work in the brightest sunlight since the
variants of channelrhodopsin have not been developed
completely. Improvement on the characteristics of the
protein is in the works. Researchers are using a computer model to investigate
what the goals for the channelrhodopsins are.
http://www.sciencedaily.com/releases/2013/11/131127225344.htm
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