Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about factors that induce this reprogramming. Induced pluripotent stem cells have only been in the stem cell relm since early in 2010. The advantages to using iPsc's is that you have a gentic match to the donor because the cells come from within the host. Gentic Equivelence is the attribute that allows for this to occur in stem cell differentiation. Theoretically if proven successful any cell in the body will be able to be derrived.

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