Team creates 'engineered organ' model for breast cancer research

Researchers are Purdue have engineered a new model for breast cancer research. This new model mimics the branching mammary duct system, where most breast cancers begin. By using this new model with nanoparticles, the team hopes to be able to detect and target tumor cells within ducts of a natural breast.

The team plans to introduce magnetic nanoparticles through the opening of the nipple. By using a magnetic field, they will be able to guide the nanoparticles through the ducts where they could attach to cancer cells and deliver anticancer agents directly to the cancer cells. By using nanoparticles, a smaller tumor size can be identified. This results in finding cancer much more earlier.

Currently, the team has been able to successfully grow cells that line the mammary ducts within the mold. They have also been able to move nanoparticles within the bare channels of the mold filled with fluid. Future research involves moving the nanoparticles through the finished model lined with living cells.

This is interesting research due to its potential to identify breast cancer early, and its ability to target cancer cells within the ducts. This study offers a new perspective on how to identify and treat a common cancer in women.

http://www.physorg.com/news/2011-01-team-breast-cancer.html