New DNA Tests for Colon Cancer

Colon cancer is disgnosed in over 150,000 people per year in the US and cost a great deal for treatment. Recent studies have shown that two new DNA tests can be performed so that colonoscopies can be perscribed for people only if one of these tests has returned positive. Colonoscopies are a process in which the colon (the large intestine) and the rectum are examined with a colonoscope. All people of the age of 50 are currently being referred routinely to have this test performed.

The theory is that more people would be more likely to take these new DNA tests since they are a non-invasive, less expensive, and a more effective way to diagnose colon cancer since colonoscopies can often miss tumors in the upper large intestine.

The first DNA test would examine stool samples for four altered genes, that if present, could signify colon cancer and can allow doctors to find and remove tumors at an early age. The second test examines the blood for an altered Septin 9 gene found in colon cancer patients.

There is question to whether or not the tests are sensitive enough to detect the harmful tumors and specific enough to not give inaccurate results. Once the trial of the tests is finished, the tests will be available around 2012 (if approved).

http://www.nytimes.com/2010/10/29/health/29cancer.html?ref=research