Alzheimer's In Mice

In a study published in Nature, a possible new treatment for Alzheimer's was tested on mice. The new drug is called a histone deacetylase (HDAC) inhibitor. This drug produces the same result in mice as the "enriched environment" therapy, which helps stimulate memory recovery by means of a healthy, enjoyable environment. The drug makes the mouse's brain produce more synapses and dendrites in order to reverse the disease's effects. The success of this drug in mice with brain atrophy -- similar to Alzheimer's -- seems to indicate that degenerative brain disorders do not completely destroy old memories, merely that they prevent access to the stored memories. If this were true, it would mean that even advanced stages of these brain disorders could be treated successfully.

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