Fibulin-2 Assists in Cardiac Tissue Remodeling

A malignant side effect of myocardial infarction is the severe, lasting damage to the myocardium. Recent research at Thomas Jefferson University identifies an extracellular protein known as Fibulin-2 that contributes to the wound healing process. In a study of mice, acute healing is delayed in mice lacking Fibulin-2, thus resulting in a larger area of cardiac damage for those mice. Future implementations of the experimental results include a better understanding of chronic heart failure.

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