Monday, November 13, 2006

Scientists design a PSA-activated protoxin that kills prostate cancer

Scientists based at John Hopkins University have discovered a protein made by cancerous prostate cells that has the potential to target and kill the prostate tissue itself. The protoxin, called PRX302, is made from an inactive molecule called proaerolysin.
Tests are still in their early stages but, in monkeys, have shown from 25-50% reduction of the prostate tissue when a sample of the protein was injected directly into the gland. Another important find of the tests is that the damage was limited to only the prostate and not the surrounding tissues.
This article is of interest to me because as a male, I am at an increased risk of getting prostate cancer as I age. Nearly 220,000 men die each year from prostate cancer. Any treatment that has the potential to reduce that number and save lives is a treatment that I am interested in.

http://www.eurekalert.org/pub_releases/2006-11/eofr-sda110906.php

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